Insulin
Administration

Made
Needle-Free

Already launched in Canada, the UK and in France, InsuJet™ offers needle-free insulin delivery to people with diabetes available in Europe.

Thanks to its jet injection technology, it optimizes insulin absorption, and allows you to perform your injections safely!

Traditional injection versus InsuJet™

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How does it work?

Applied to the skin, InsuJet™ delivers insulin in a thin jet injection that easily penetrates the skin, ensuring optimal distribution into the subcutaneous tissue.

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Needle-free delivery

  • Eliminates needle anxiety
  • Removes the risk of needle stick injury
  • No sharps waste
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Faster and effective absorption

  • Optimized peak action
  • Improved glycemic control
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Better for the environment

  • Sustainable: reusable device for up to 5,000 injections
  • 1 nozzle replaces 56 insulin syringes or pen-needles

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FAQ

Who can use InsuJet™?

The InsuJet™ is intended for adults with type 1 or type 2 diabetes who require subcutaneous insulin injections. We recommend consulting a healthcare professional before starting to use the device.

Why is needle-free injection especially suitable for people with a higher BMI?

With InsuJet™, the insulin peak action is reached 30% faster, regardless of the patient's BMI. This enables quicker correction of hyperglycemic episodes — a particularly valuable benefit for overweight patients.

What are the benefits of faster insulin absorption with InsuJet™?

Insulin delivered with InsuJet™ is absorbed more quickly than with a pen, reaching its peak action about 40 minutes earlier. This means it starts working faster, helping to better control postprandial (after-meal) blood sugar spikes.

How does the InsuJet™ device deliver insulin?

By rotating the rear part of the InsuJet™, a spring is compressed to prime the mechanism. Once released, this spring propels the insulin through a small orifice located on the nozzle, generating a very fine, high-pressure jet. This jet passes through the skin without a needle and allows the insulin to be deposited directly into the subcutaneous tissue.

What types of insulin can be used with the InsuJet™?

The InsuJet™ can be used with all types of 100 IU/ml insulin.

  • Human and animal insulin (in countries where it is still available)
  • Rapid-acting (bolus) insulins and rapid-acting insulin analogs
  • Basal (long-acting) insulins: intermediate (NPH, isophane) and long-acting insulins
  • Premixed insulins: human insulin 30/70 and mixtures of rapid-acting and intermediate analogs

If in doubt, please consult your diabetes care provider.

What doses of insulin can be administered with the InsuJet™?

The current version of the InsuJet™ can be used to inject 4 to 50 Insulin Units per administration. Insulin in not provided with the system.

Can I use the same device for long-acting and rapid-acting insulin?

The same Nozzle should never be used to administer different types of insulin. After each administration, a small insulin residue will remain inside the Nozzle. This residue affects the composition of the subsequent administration. Especially when long- and short acting insulins are alternated, this might lead to unexpected results.
For your convenience, we recommend using a separate InsuJet™ device for each type of insulin. Labels with different colours are included in the package. You can use these labels to easily identify the separate devices, as well as their Carry Cases.

Which insulin vial and cartridge sizes are suitable with the InsuJet™?

There are two types of InsuJet™ adapters for withdrawing insulin from:

  • 3 mL cartridges
  • Disposable insulin preloads
  • 10 mL vials

What is the diameter of the jet emitted through the nozzle?

The InsuJet™ device's tip orifice is 0.15 mm in diameter, which is much smaller than conventional needle gauges used for subcutaneous insulin administration. For comparison, a standard needle gauge is approximately 0.40 to 0.45 mm in diameter. The added ring (which comes with the tips) helps improve injection comfort.

Is needle-free injection painless?

Although this device is often painless to use, you may occasionally feel a slight pinch, similar to the experience with small needles. For optimal comfort, ensure the insulin being injected is at room temperature and use the InsuJet™ comfort ring.

Will the InsuJet™ cause skin blistering or any other complications?

The InsuJet™ may be used, but with caution, by anyone who bruises or bleeds easily. In
the event of excessive bruising the usage of the InsuJet™ should be discontinued. The InsuJet™ will normally not cause blistering, but anyone who has a skin condition associated with the administration sites to be used, should consult his Diabetes Care Specialist before switching to the InsuJet™

I currently use another insulin delivery device. Can I switch to the InsuJet™?

Absolutely. You can switch to InsuJet™ on the recommendation of your specialist. As with any change in your diabetes management, the period of switching to InsuJet™ should be carefully monitored in consultation with your diabetes treatment specialist.

What is the difference between the Model M and the Model S?

The difference between the M (moderate) and S (soft) models lies in the pressure applied to the insulin by the mechanism: 30-40MPa for the M injector and 20-25MPa for the S. The pressure range applied in the M model is suitable for most adults. The S model is intended for children as well as people with thinner skin.

If you purchased a Model S and your injections are wet, contact us as this means you need a Model M.

Bibliography

Engwerda EE, Tack CJ, de Galan BE. Needle-free jet injection of rapid-acting insulin improves early postprandial glycemic control in patients with diabetes. Diabetes Care. 2013;36(11):3436-3441. doi:10.2337/dc13-0492.

Galan BE, Engwerda EE, Abbink EJ, Tack CJ. Body mass index and the efficacy of needle-free jet injection for the delivery of rapid-acting insulin analogs: a post hoc analysis. Diabetes Obes Metab. 2013;15(1):84-86. doi:10.1111/j.1463-1326.2012.01666.x.

Wit HM, Engwerda EE, Tack CJ, de Galan BE. Insulin delivery by needle-free jet injection more rapidly corrects marked hyperglycemia in overweight or obese diabetic patients. Diabetes Obes Metab. 2015;17(11):1093-1099. doi:10.1111/dom.12550.

Reutens AT, Balkau B, Cohen N. A pilot study of device tolerability and preference in patients with type 1 diabetes, comparing insulin aspart delivery by InsuJet™ with subcutaneous injection. Diabetes Technol Ther. 2014;16(4):235-240. doi:10.1089/dia.2013.0250.

Engwerda EE, Abbink EJ, Tack CJ, de Galan BE. Improved pharmacokinetic and pharmacodynamic profile of rapid-acting insulin using needle-free jet injection technology. Diabetes Care. 2011;34(8):1804-1808. doi:10.2337/dc11-0182.